Offense
- QB: Lamar Jackson, Baltimore Ravens
- RB: Rhamondre Stevenson, New England Patriots
- WR: Amon-Ra St. Brown, Detroit Lions
- WR: Zay Flowers, Baltimore Ravens
- TE: Tyler Higbee, Los Angeles Rams
- Flex: WR Ja'Marr Chase, Cincinnati Bengals
- LT: Tristan Wirfs, Tampa Bay Buccaneers
- LG: Grey Zabel, Seattle Seahawks
- C: Aaron Brewer, Miami Dolphins
- RG: Joe Tippmann, New York Jets
- RT: Ryan Van Demark, Buffalo Bills
Defense
- EDGE: Carl Granderson, New Orleans Saints
- EDGE: Aidan Hutchinson, Detroit Lions
- DI: Kobie Turner, Los Angeles Rams
- DI: Zach Allen, Denver Broncos
- LB: Nick Bolton, Kansas City Chiefs
- LB: Jeremiah Trotter Jr., Philadelphia Eagles
- CB: Dee Alford, Atlanta Falcons
- CB: Jarrian Jones, Jacksonville Jaguars
- S: Nick Scott, Carolina Panthers
- S: Antonio Johnson, Jacksonville Jaguars
- Flex: CB Ja'Quan McMillian, Denver Broncos
Special teams
- K: Cam Little, Jacksonville Jaguars
- P: Matt Araiza, Kansas City Chiefs
- ST: Tavierre Thomas, Minnesota Vikings
- K/PR: Keaton Mitchell, Baltimore Ravens
Offensive Player of the Week: RB Rhamondre Stevenson, New England Patriots
Fighting for carries heading into the playoffs, Stevenson made the most of his limited carries, turning seven attempts into 131 yards and a pair of touchdowns while forcing four missed tackles along the way. He also made an impact as a receiver, adding another 22 yards and a third touchdown. He finished the game with a 92.9 PFF grade.
Defensive Player of the Week: EDGE Carl Granderson, New Orleans Saints
Granderson was effective as a pass-rusher, as he registered five pressures from 27 pass-rushing snaps, and run defender, as he registered four tackles resulting in a defensive stop, but he made one of the plays of the week in coverage. Reading the play and peeling off from his original pass-rush, he made an incredible interception on a screen pass, jumping in front of the throw by Atlanta Falcons quarterback Kirk Cousins.
Rookie of the Week: G Grey Zabel, Seattle Seahawks
It’s rare for an offensive lineman to be named here, but Zabel led all rookies in PFF grade this week after an outstanding performance in their NFC West clinching win over the San Francisco 49ers. Along with not allowing a pressure from 32 pass-blocking snaps, Zabel also earned a 91.6 PFF run-blocking grade.
Offensive Line of the Week: Buffalo Bills
The Bills offensive line shut down the New York Jets‘ pass-rush in Week 18, as the offensive line surrendered just one pressure from 32 pass-blocking snaps in the game. It also helped fuel a huge game on the ground, as the Bills racked up 211 rushing yards.