The teams split their regular-season series, with Seattle rallying for a dramatic 38-37 overtime win in December and Los Angeles taking the earlier matchup.
At the center of it is a fascinating quarterback contrast. Matthew Stafford has played at an elite level this season, earning a 91.6 PFF grade with a 7.0% big-time throw rate and strong efficiency both from clean pockets (116.9 passer rating) and under pressure (78.1). Sam Darnold has been steadier than spectacular for Seattle, posting a 79.9 PFF grade while limiting mistakes with a matching 3.3% turnover-worthy play rate.
Below, we break down the spread, moneyline and total using PFF's market data, compare the two starting quarterbacks through stable efficiency metrics and highlight the team-level advantages that could swing this game.
This preview also dives into notable injuries, trench mismatches and unit-level grades that matter most on Sunday, with all data powered by PFF Premium Stats and betting projections.